Lintho tsa tlhaho tsa lik'hemik'hale | 6-Bromo-7-methoxy-1,1-dimethyl-3,4-dihydronaphthalen-2(1H)-one ke mokelikeli o bonaletsang o se nang 'mala ho isa ho o mosehla o khanyang, o sa qhibiliheng metsing, o qhibilihang ho CHCl3, polokelo e lokela ho ba leqhoa, e arohane le li-oxidants, lik'hemik'hale tse jeoang, hole le mollo, mohloli oa mocheso. | |
Lisebelisoa | 6-Bromo-7-methoxy-1,1-dimethyl-3,4-dihydronaphthalen-2(1H)-oneke inhibitor e mahareng ea Alectinib, e khethang haholo le e matla ea anaplastic lymphoma kinase (ALK) inhibitor e khonang ho thibela phetoho ea molebeli oa heke e hanyetsanang, e leng se fellang ka ho fokotseha ha kholo ea lisele. | |
Sebopeho sa mmele | Seedi se se nang mmala ho isa ho bosehla | |
Shelf bophelo | Ho latela boiphihlelo ba rona, sehlahisoa se ka bolokoa bakeng sa 12likhoeli ho tloha ka letsatsi la ho pepa haeba li bolokiloe ka lijaneng tse tiisitsoeng ka thata, li sirelelitsoe leseli le mocheso 'me li bolokiloe mocheso o pakeng tsa 5 -30°C. | |
Tlitšobotsi tse tšoanang
| Ntlha e belang | 354.7±42.0 °C ho 760 mmHg |
Flash point | 168.3±27.9 °C | |
Hantle-ntle 'Misa | 282.025543 | |
PSA | 26.30000 | |
LogP | 3.25 | |
Khatello ea Mouoane | 0.0±0.8 mmHg ho 25°C | |
Index ea Refraction | 1.545 | |
pka | 1.26±0.10(E boletsoeng esale pele) | |
Ho qhibiliha ha Metsi | 50 mg/ml ho CHCl3 |
Ha o sebetsana le sehlahisoa sena, ka kopo latela likeletso le tlhaiso-leseling e fanoeng leqepheng la polokeho 'me u shebe mehato ea ts'ireletso le bohloeki sebakeng sa mosebetsi e lekaneng ho sebetsana le lik'hemik'hale.
Lintlha tse bukeng ena li thehiloe tsebong le phihlelong eo re nang le eona hona joale.Ka lebaka la lintlha tse ngata tse ka amang ts'ebetso le ts'ebeliso ea sehlahisoa sa rona, lintlha tsena ha li lokolle li-processor ho etsa lipatlisiso le liteko tsa bona;leha e le hore lintlha tsena ha li fane ka maikutlo a tiisetso ea thepa e itseng, kapa ho nepahala ha sehlahisoa ka morero o itseng.Litlhaloso leha e le life, litšoantšo, lifoto, lintlha, boholo, boima, joalo-joalo tse fanoeng mona li ka fetoha ntle le boitsebiso ba pele 'me ha li thehe boleng ba konteraka boo ho lumellanoeng ka bona ba sehlahisoa.Boleng ba konteraka boo ho lumellanoeng ka bona ba sehlahisoa bo hlahisoa ka mokhoa o ikhethileng ho tsoa ho litatemente tse entsoeng ho latela lintlha tsa sehlahisoa.Ke boikarabello ba moamoheli oa sehlahisoa sa rona ho netefatsa hore litokelo life kapa life tsa botho le melao le melao e teng ea hlokomeloa.