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6-Bromo-7-methoxy-1,1-dimethyl-3,4-dihydronaphthalen-2(1H)-one

Tlhaloso e Khutšoanyane:

Lebitso la lik'hemik'hale: 6-Bromo-7-methoxy-1,1-dimethyl-3,4-dihydronaphthalen-2(1H)-one

CAS: 1256578-99-0

Foromo ea lik'hemik'hale: C13H15BrO2

Boima ba molek'hule: 283.16

Boima: 1.3±0.1g/cm3

Sebaka se belang: 354.7±42.0 ℃ (760 mmHg)

 


Lintlha tsa Sehlahisoa

Li-tag tsa Sehlahisoa

Tlhaloso ea Sehlahisoa

Lintho tsa tlhaho tsa lik'hemik'hale

6-Bromo-7-methoxy-1,1-dimethyl-3,4-dihydronaphthalen-2(1H)-one ke mokelikeli o bonaletsang o se nang 'mala ho isa ho o mosehla o khanyang, o sa qhibiliheng metsing, o qhibilihang ho CHCl3, polokelo e lokela ho ba leqhoa, e arohane le li-oxidants, lik'hemik'hale tse jeoang, hole le mollo, mohloli oa mocheso.

Lisebelisoa

6-Bromo-7-methoxy-1,1-dimethyl-3,4-dihydronaphthalen-2(1H)-oneke inhibitor e mahareng ea Alectinib, e khethang haholo le e matla ea anaplastic lymphoma kinase (ALK) inhibitor e khonang ho thibela phetoho ea molebeli oa heke e hanyetsanang, e leng se fellang ka ho fokotseha ha kholo ea lisele.

Sebopeho sa mmele

Seedi se se nang mmala ho isa ho bosehla

Shelf bophelo

Ho latela boiphihlelo ba rona, sehlahisoa se ka bolokoa bakeng sa 12likhoeli ho tloha ka letsatsi la ho pepa haeba li bolokiloe ka lijaneng tse tiisitsoeng ka thata, li sirelelitsoe leseli le mocheso 'me li bolokiloe mocheso o pakeng tsa 5 -30°C.

Tlitšobotsi tse tšoanang

Ntlha e belang

354.7±42.0 °C ho 760 mmHg

Flash point

168.3±27.9 °C

Hantle-ntle 'Misa

282.025543

PSA

26.30000

LogP

3.25

Khatello ea Mouoane

0.0±0.8 mmHg ho 25°C

Index ea Refraction

1.545

pka

1.26±0.10(E boletsoeng esale pele)

Ho qhibiliha ha Metsi

50 mg/ml ho CHCl3

 

 

Polokeho

Ha o sebetsana le sehlahisoa sena, ka kopo latela likeletso le tlhaiso-leseling e fanoeng leqepheng la polokeho 'me u shebe mehato ea ts'ireletso le bohloeki sebakeng sa mosebetsi e lekaneng ho sebetsana le lik'hemik'hale.

 

Hlokomela

Lintlha tse bukeng ena li thehiloe tsebong le phihlelong eo re nang le eona hona joale.Ka lebaka la lintlha tse ngata tse ka amang ts'ebetso le ts'ebeliso ea sehlahisoa sa rona, lintlha tsena ha li lokolle li-processor ho etsa lipatlisiso le liteko tsa bona;leha e le hore lintlha tsena ha li fane ka maikutlo a tiisetso ea thepa e itseng, kapa ho nepahala ha sehlahisoa ka morero o itseng.Litlhaloso leha e le life, litšoantšo, lifoto, lintlha, boholo, boima, joalo-joalo tse fanoeng mona li ka fetoha ntle le boitsebiso ba pele 'me ha li thehe boleng ba konteraka boo ho lumellanoeng ka bona ba sehlahisoa.Boleng ba konteraka boo ho lumellanoeng ka bona ba sehlahisoa bo hlahisoa ka mokhoa o ikhethileng ho tsoa ho litatemente tse entsoeng ho latela lintlha tsa sehlahisoa.Ke boikarabello ba moamoheli oa sehlahisoa sa rona ho netefatsa hore litokelo life kapa life tsa botho le melao le melao e teng ea hlokomeloa.


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