6-Bromo-7-methoxy-1,1-dimethyl-3,4-dihydronaphthalen-2(1H)-one
| Litšobotsi tsa lik'hemik'hale | 6-Bromo-7-methoxy-1,1-dimethyl-3,4-dihydronaphthalen-2(1H)-one ke mokelikeli o bonaletsang o se nang 'mala ho isa ho o mosehla o bobebe, o sa qhibiliheng metsing, o qhibilihang ka har'a CHCl3, polokelo e lokela ho hoamisoa, e aroloe ho di-oxidant, dikhemikhale tse jewang, hole le mollo, le mohlodi wa mocheso. | |
| Likopo | 6-Bromo-7-methoxy-1,1-dimethyl-3,4-dihydronaphthalen-2(1H)-oneke karolo e bohareng ea Alectinib, e leng inhibitor e matla le e khethang haholo ea anaplastic lymphoma kinase (ALK) e khonang ho thibela phetoho ea gatekeeper e sa haneleng, e leng se fellang ka kholo e fokotsehileng ea lisele. | |
| Sebopeho sa 'mele | Mokelikeli o se nang 'mala ho isa ho o mosehla | |
| Nako ea ho boloka lintho | Ho ea ka phihlelo ea rona, sehlahisoa se ka bolokoa bakeng sa matsatsi a 12.likhoeli ho tloha letsatsing la ho tlisoa haeba li bolokiloe ka har'a lijana tse koetsoeng ka thata, li sirelelitsoe khanyeng le mochesong 'me li bolokiloe mochesong o pakeng tsa 5 -30°C. | |
| Tthepa ea tlhaho
| Sebaka sa ho bela | 354.7±42.0 °C ho 760 mmHg |
| Flash point | 168.3±27.9 °C | |
| Boima bo nepahetseng | 282.025543 | |
| PSA | 26.30000 | |
| LogP | 3.25 | |
| Khatello ea mouoane | 0.0±0.8 mmHg ho 25°C | |
| Index ea Refraction | 1.545 | |
| pka | 1.26±0.10 (E boletsoeng esale pele) | |
| Ho qhibiliha ha metsi | 50 mg/ml ka CHCl3 | |
Polokeho
Ha o sebetsana le sehlahisoa sena, ka kopo latela keletso le tlhahisoleseding e fanoeng leqepheng la data la polokeho mme o latele mehato ya tshireletso le bohloeki ba sebaka sa mosebetsi e lekaneng bakeng sa ho sebetsana le dikhemikhale.
Hlokomela
Lintlha tse ka har'a khatiso ena li ipapisitse le tsebo le boiphihlelo ba rona ba hona joale. Ka lebaka la lintlha tse ngata tse ka amang ts'ebetso le ts'ebeliso ea sehlahisoa sa rona, lintlha tsena ha li lopolle bahlaseli ho etsa lipatlisiso le liteko tsa bona; leha e le hore lintlha tsena li fana ka tiiso efe kapa efe ea thepa e itseng, kapa ho tšoaneleha ha sehlahisoa bakeng sa morero o itseng. Litlhaloso life kapa life, litšoantšo, linepe, lintlha, litekanyo, jj. tse fanoeng mona li ka fetoha ntle le tlhaiso-leseling ea pele 'me ha li thehe boleng bo lumellanoeng ba konteraka ea sehlahisoa. Boleng bo lumellanoeng ba konteraka ea sehlahisoa bo hlaha feela lipolelong tse entsoeng tlhalosong ea sehlahisoa. Ke boikarabello ba moamoheli oa sehlahisoa sa rona ho netefatsa hore litokelo life kapa life tsa beng ba sona le melao le melao e teng lia bolokoa.
